Interactions of proteins with DNA are required to maintain genome stability and to control DNA replication and repair, chromosome segregation and gene expression. Chromatin immunoprecipitation (ChIP) ...

Biotium, a leading developer of fluorescent reagents for life science research, announces the launch of the RNaseReveal™ Activity Assay Kit, with unparalleled sensitivity to detect RNase contamination ...

Laboratory automation typically involves integrating key instrumentation with liquid- and microplate-handling robots creating workcells that are often designed for a single protocol. The scheduling ...

Therapeutic antibodies are now the major class of successful protein drugs with many more in development to target a variety of major diseases. An important and desirable biological activity of most ...

insights from industryDr. Lindsay ParkesSenior Research ScientistPorvair Sciences An Interview with Dr. Lindsay Parkes, Senior Research Scientist, Porvair Sciences In the past decade there have been ...

A new ultrabright fluorescent label might make bioassays faster and more sensitive. Srikanth Singamaneni and coworkers at Washington University in St. Louis make their “plasmonic-fluor” labels of a ...

An increasing body of research indicates that more translational and relevant evaluations can be made utilizing 3D organoids and micro-tissues as opposed to 2D monolayer cell models. This is most ...

This is a protocol for culturing MDCK cells (an epithelial cell line derived from the canine kidney) in a monolayer and assessing Trans-Epithelial Electrical Resistance (TEER) and Aβ transport.

Enzyme assays are essential tools for understanding how enzymes function, from drug discovery to food science. Careful control of assay conditions, awareness of kinetic complexities, and adoption of ...