The mammalian diaphanous-related formins (mDIAs), originally characterized for their ability to nucleate unbranched actin, can also regulate microtubule stabilization during cell polarization and ...

Researchers have visualized at the molecular level how formins bind to the ends of actin filaments. This allowed them to uncover how formins mediate the addition of new actin molecules to a growing ...

Bolted climb put up by Bruno Sartorelli and Danilo Serafini up the second bastion of Mondeval, the beautiful pillar that together with the others forms the sunny south Face of Lastoni di Formin. Park ...

Love my dogs (7a, 300m), new route on Lastoni di Formin (Dolomites) by Mario Dibona and Gretchen Alexander. New route on the Lastoni di Formin (Dolomites) at the hands of Mario Dibona and Gretchen ...

Our lab is focused on the question of how cells dynamically assemble and reorganize their actin cytoskeletons to govern cell shape, cell movement, and cell division. Every cell type has a unique ...

There is increasing evidence that post-traumatic stress disorder (PTSD) increases the risk of developing dementia later in life. Researchers now shed light on the molecular mechanism that links the ...

Formins are made of two identical parts (red, orange) that encircle the actin (grey) filament in a ring-like conformation. “Our discovery allows us to interpret decades of biochemical studies on ...