The enteric nervous system (ENS) is a sophisticated, autonomous network of neurons and glia embedded within the gastrointestinal tract, critical for regulating motility, secretion, and blood flow. The ...

In about one out of every 1,000 pregnancies, the neural tube, a key nervous system structure, fails to close properly.

The Wistar Institute's Alessandro Gardini, Ph.D., and lab have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular "bridge" ...

When do peripheral nerves develop? Researchers used "mosaic barcodes" to prove that neural crest cells commit to their ...

Researchers from the lab of Richard Simerly have uncovered the first example of activity-dependent development of hypothalamic neural circuitry. The work also suggests a novel role for the hunger ...

The Wistar Institute's Alessandro Gardini, Ph.D., and lab have shed new light on how certain biological processes determine ...

Millions of neurons branch throughout our bodies, keeping them in close communication with our brains. This peripheral ...

Recent advances in genomics, genome editing, and imaging technologies have revealed that neural activity can rapidly alter chromatin accessibility, ...

How does the neural tube close? A new study uses physics-based modeling to reveal the actin "purse-string" mechanism and cellular coordination that prevents spina bifida.

Neural organoids have been heralded as having huge potential for advancing our knowledge of the brain in several fields. These include exploring the responses of brain tissue to drugs, investigating ...

In 2020, researchers engineered living, programmable organisms from Xenopus laevis, calling them xenobots, which could self-assemble and even reproduce. Building on this work, scientists later ...