A mutation in the TDP-43 protein reduces the viability of motor neurons without triggering protein clumps, researchers found.

Dosing has begun in a new regimen of the HEALEY ALS platform trial, its ninth, which is testing the oral therapy NUZ-001 for ...

ALS has resulted in significant losses for columnist Kristin Neva's husband, Todd, but the smaller losses prick at her heart, too.

Fat-based vesicles help deliver GM1 to the brain, improving movement and extending survival in mouse models of ALS, a study finds.

AB Science says a newly identified blood biomarker may help assess masitinib activity in its ongoing Phase 3 ALS clinical ...

Rather than worrying about bucket list adventures, columnist Juliet Taylor and her late husband, Jeff, focused on friends and ...

Being diagnosed with ALS has changed many of the assumptions that columnist Justin Ramirez had about fatherhood, but he still remains "Dad." ...

Blood lactate levels were associated with survival and weight changes in ALS, according to a study in Australia and Japan.

Next week, researchers, clinicians, industry leaders, and families will gather at the 2026 MDA Clinical & Scientific Conference, hosted by the Muscular Dystrophy Association (MDA), to discuss the ...

Early birds are at a significantly lower risk of developing amyotrophic lateral sclerosis (ALS) than night owls, according to a new study.

Columnist Dagmar Munn once kept busy with multitasking, but living with ALS has taught her the value of slowing down.

A UNLV scientist was named the winner of the inaugural MDA Research Momentum Award for his work investigating the underlying causes of ALS.