A375, HEK293T, Sk-Mel-3 and Sk-Mel-24 cell lines were obtained from the American Type Culture Collection. A375 and HEK293T cells were maintained in ...

Researchers developed a gorilla adenovirus platform with inherent tumor selectivity, lung tropism, and large-gene capacity.

The first-ever clinical trial of an adeno-associated virus (AAV) gene therapy for type 1 diabetes (T1D) is set to begin this year. The PROGRESS study will enroll adults with T1D to receive a one-time ...

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally evolved gene-editing system that can activate genes, offering an advantage ...

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health traits. By probing regions of DNA previously linked to disease, the work has ...

BEVERLY, Mass.--(BUSINESS WIRE)--seqWell, a global leader in NGS library construction technology, today announced the launch of MosaiX, a next-generation library prep kit designed to streamline a wide ...

In previous work, researchers from CEINGE (Naples, Italy) and collaborating institutions developed an alternative gene therapy strategy based on the expression of a secreted fusion protein, including ...

After facing a delayed decision deadline and a clinical hold, Regenxbio’s Hunter syndrome gene therapy has been rejected by the FDA. In rejecting RGX-121, the FDA raised concerns about its clinical ...

SynGenSys, a biotechnology company designing synthetic gene promoter systems to address critical bottlenecks in biopharma manufacturing and enhance cell and gene therapy development, today announced ...

Validated, tissue-specific library enables customisable and controllable liver-targeted gene expression with high specificity and minimal off-target activity in muscle tissue SynGenSys, a ...

Real-World Plasma Thymidine Kinase Activity in High-Risk and Metastatic Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Treated With Cyclin-Dependent Kinase ...

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to increased knowledge about gene regulation in human cells. How genes are turned on ...